Oxidative damage is one of the hallmarks of the aging process. The current study evaluated effects of two proprietary antioxidant-based ingredients, rosemary extract and spearmint extract containing carnosic acid and rosmarinic acid, respectively, on learning and memory in the SAMP8 mouse model of accelerated aging. The two rosemary extracts contained carnosic acid and one spearmint extract contained 5% rosmarinic acid. Three doses of actives in each extract were tested: 32, 16, 1.6 or 0 mg/kg. After 90 days of treatment mice were tested in T-maze foot shock avoidance, object recognition and lever press. Rosemary extract containing 60% carnosic acid improved acquisition and retention in T-maze foot shock, object recognition and lever press. Rosemary extract with 10% carnosic acid improved retention in T-maze foot shock avoidance and lever press.
一旦焦虑情绪爆发,通常伴有心理和躯体疾病,例如自主神经觉醒、烦躁、疲劳、注意力不集中、易怒和睡眠问题,让你紧张不安、失眠脱力,工作效率和生活质量下降,更甚至记忆力退化,给个人和社会都带来了巨大的健康和经济代价。
最近发表在期刊《Journal of Neurology》上的一篇文章,研究了炎症对认知的影响,研究人员跟踪了12366名受试者大约20年,然后进行认知评估测试,发现具有炎症标志物的受试者在20年来认知功能下降幅度最大。